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Master of Science in

Computational Biology

Overview

The goal of the program is to equip students with knowledge and skills in both biology and computational sciences, including programming, machine learning, statistics, and bioinformatics. The program prepares students for collaborative work with biologists, chemists, and clinicians by fostering interdisciplinary communication and teamwork. The program aims to prepare students to join the workforce in biotechnology and healthcare or to pursue a PhD. The program supports the development of the UAE biotechnology and health ecosystem by developing a highly skilled workforce in computational biology and bioinformatics. It makes significant contributions to both the academic world and the broader scientific community while supporting the UAE societal and economic goals and transformation agenda, and bridges gaps between disciplines and industries and build a collaborative platform for the UAE biotechnology and healthcare ecosystem, with strong connections to the state-of-the-art international biotechnology research and industry.

  • icon Full time Mode
  • icon 36 credits
  • icon On Campus Location

Deadlines for applications for Fall 2026:
15 January 2026 (5:00pm UAE time)

Welcome to the Department of Computational Biology at Mohamed bin Zayed University of Artificial Intelligence (MBZUAI).... Join us at MBZUAI in advancing the critical synergy between bioinformatics, biology and computational sciences.

Eran Segal

Department Chair and Professor of Computational Biology

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Meet the faculty

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Aziz Khan

Assistant Professor of Computational Biology

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Eduardo Beltrame

Assistant Professor of Computational Biology

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Imran Razzak

Associate Professor of Computational Biology

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Natasa Przulj

Professor of Computational Biology

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Yu Li

Affiliated Assistant Professor of Computational Biology

  • PLO 01: Design scientific experiments, especially those related to biological systems, using the scientific method.
  • PLO 02: Apply computational tools and technologies, including Artificial Intelligence, to solving problems of varying complexity, especially computational and experimental tools and methods utilized in life sciences, biotechnology and healthcare.
  • PLO 03: Utilize methods and tools to integrate, analyze and interpret biological data from various sources, respecting ethical norms and personal data privacy.
  • PLO 04: Function effectively as a member or leader of a team engaged in collaborative research projects.
  • PLO 05: Appraise and communicate data and scientific findings effectively to any audience, orally, visually, and in written format, individually or in teams.

The minimum degree requirements for the Master of Science in Computational Biology program is 36 Credits, distributed as follows:

Number of Courses Credit Hours
Core 4 16
Electives 2 8
Internship At least one internship of up to six weeks duration must be satisfactorily completed as a graduation requirement 2
Introduction to Research Methods 1 2
Research Thesis 1 8

The Master of Science in Computational Biology program is primarily a research-based degree. The purpose of coursework is to equip students with the right skill set, so they can successfully accomplish their research project (thesis). Students are required to take CB7103, CB7104, CB7105 and CB7106 as mandatory courses. All students must take the following courses:

Code Course title Credit hours
CB7103 Introduction to Single Cell Biology and Bioinformatics

This course provides a broad overview of bioinformatics for single cell omics technologies, a new and fast-growing family of biological assays that enables measuring the molecular contents of individual cells with very high resolution and is key to advancing precision medicine. The course starts with an accessible introduction to basic molecular biology: the cell structure, the central dogma of molecular biology, the flow of biological information in the cell, the different types of molecules in the cell, and how we can measure them. This course then introduces students to the diverse landscape of biological data, including its types and characteristics and explores the foundational principles of single-cell omics bioinformatics, encompassing key methodologies, tools, and computational workflows, with an emphasis on the development of foundation models for single cell omics data

4
CB7104 Introduction to molecular biology for machine learning

This interdisciplinary course is designed for students and professionals with a background in machine learning who seek to understand the fundamentals of molecular biology. The course explores key biological concepts and their applications to machine learning, particularly in the fields of bioinformatics, genomics, and computational biology. By bridging the gap between molecular biology and machine learning, students will gain the knowledge to apply machine learning techniques to biological data and solve complex problems in medicine, genetics, and drug discovery.

4
CB7105 Analyzing Multi-Omics Network Data in Biology and Medicine

Computational biology has become an important discipline in the intersection of computing, mathematics, biology and medicine. Biological data sets produced by modern biotechnologies are large and hence they can only be understood by using mathematical modeling and computational techniques. Starting from analysis of genetic sequences, the field has progressed towards analysis and modeling of entire biological systems. A way of abstracting the vast amount of biomedical information is by modeling and analyzing these data by using networks (or graphs). Such approaches have been used to model phenomena in other research domains, apart from computational and systems biology and medicine.

4
CB7106 Computational Genomics and Epigenomics

This interdisciplinary graduate course introduces students to the core concepts, tools, and emerging methods in computational genomics and epigenomics. It is designed for students from biology, computer science, machine learning, and related fields who are interested in applying their skills to cutting-edge questions in biology and medicine. Students will explore how genomic and epigenomic data, such as DNA, RNA, chromatin accessibility, and methylation, are generated and analyzed using statistical and machine learning techniques. The course covers foundational topics such as genome organization, gene regulation, and high-throughput sequencing technologies. It extends to advanced applications including multi-omic data integration, deep learning for genomics, and cancer omics.
Course description: This course examines the intersection of artificial intelligence (AI) and computer systems, focusing on how systems enable efficient AI workloads and how AI techniques enhance system performance. The course covers fundamental principles and emerging trends in system design, hardware-software co-design, resource management, and AI-driven system optimization. Through lectures, hands-on labs, and research projects, students will explore techniques for scaling AI applications, improving system efficiency, and integrating AI into traditional computing environments. By engaging with real-world case studies and cutting-edge frameworks, students will develop the skills needed to contribute to the rapidly evolving field of AI systems in both academia and industry. 

4

Students will select a minimum of three elective courses, totaling twelve (or more) credit hours, based on their interests, proposed research thesis, and career aspirations, in consultation with their supervisory panel. The elective courses available for the Master of Science in Computer Science are listed in the table below:

Code Course title Credit hours
AI7101 Foundations of Artificial Intelligence

This course provides the students a comprehensive introduction to artificial intelligence. It builds upon fundamental concepts in machine learning. Students will learn about supervised and unsupervised learning, various learning algorithms, and the basics of the neural network, deep learning, and reinforcement learning.

4
AI7102 Deep Learning

This course provides a comprehensive overview of different concepts and methods related to deep learning. Students will first learn the foundations of deep learning, after which they will be introduced to a series of deep models: convolutional neural networks, autoencoders, recurrent neural network, and deep generative models. Students will work on case studies of deep learning in different fields such as computer vision, medical imaging, natural language processing, etc.

4
CV701 Human and Computer Vision

This course provides a comprehensive introduction to the basics of human visual system and color perception, image acquisition and processing, linear and nonlinear image filtering, image features description and extraction, classification, and segmentation strategies. Moreover, students will be introduced to quality assessment methodologies for computer vision and image processing algorithms.
Prerequisite courses:  CS7101 Algorithms and Data Structures 

Course description: This course discusses the advanced concepts in operating system design and implementation. The operating system provides a convenient and efficient interface between user programs and the hardware of the computer on which they run. 

4
CV702 Geometry for Computer Vision

The course provides a comprehensive introduction to the concepts, principles and methods of geometry-aware computer vision which helps in describing the shape and structure of the world. In particular, the objective of the course is to introduce the formal tools and techniques that are necessary for estimating depth, motion, disparity, volume, pose and shapes in 3D scenes.

4
CV703 Visual Object Recognition and Detection

This course provides a comprehensive overview of different concepts and methods related to visual object recognition and detection. In particular, the students will learn a large family of successful and recent state-of-the-art architectures of deep neural networks to solve the tasks of visual recognition, detection, and tracking.

4
DS701 Data Mining

This course is an introductory course on data mining, which is the process of discovering patterns in large data sets involving methods at the intersection of machine learning, statistics, and database systems.
Course description: This course provides an overview of foundational principles and contemporary topics in information security. Students will examine system protection strategies, structural security frameworks, software resilience, and detection of security threats. The course integrates theoretical concepts with practical applications to enhance the understanding of securing complex information systems. 

4
DS702 Big Data Processing

This course is an introductory course on big data processing, which is the process of analyzing and utilizing big data. The course involves methods at the intersection of parallel computing, machine learning, statistics, database systems, etc.

4
DS703 Information Retrieval

This course is an introductory course on Information Retrieval (IR). The explosive growth of available digital information (e.g., Web pages, emails, news, Tweets, Wikipedia pages) demands intelligent information agents that can sift through all available information and find out the most valuable and relevant information. Web search engines, such as Google and Bing, are several examples of such tools. This course studies the basic principles and practical algorithms used for information retrieval and text mining. It will cover algorithms, design, and implementation of modern information retrieval systems. Topics include: retrieval system design and implementation, text analysis techniques, retrieval models (e.g., Boolean, vector space, probabilistic, and learning-based methods), search evaluation, retrieval feedback, search log mining, and applications in web information management.

4
DS704 Statistical Aspect of Machine Learning / Statistical Theory

This course covers the fundamentals of theoretical statistics, which are the foundation for the analysis of the properties of machine learning algorithms. Covered topics include statistical models, statistical inference, maximum likelihood estimation, optimal hypothesis testing, decision theory and Bayesian inference, non-parametric statistics, and Bootstrap, (generalized) linear model and high dimensional statistics. All necessary tools from Probability theory: deviation inequalities, type of convergence, law of large numbers, central limit theorem, properties of the Gaussian distribution (etc) will be introduced whenever needed and their proofs given at the end of each chapter.

2
HC701 Medical Imaging: Physics and Analysis

This course provides a graduate-level introduction to the principles and methods of medical imaging, with thorough grounding in the physics of the imaging problems. This course covers the fundamentals of X-ray, CT, MRI, ultrasound, and PET imaging. In addition, the course provides an overview of 3D geometry of medical images and a few classical problems in medical images analysis including classification, segmentation, registration, quantification, reconstruction and radiomics.

4
INT799 Master of Science Internship

Assumed knowledge: Basic concepts in linear algebra, calculus, probability, and statistics. Programming in Python or similar language. 

Course description: This course provides a comprehensive introduction to natural language processing (NLP). It builds upon fundamental concepts in mathematics, specifically probability and statistics, linear algebra, and calculus, and assumes familiarity with programming. 

4
ML701 Machine Learning

This course provides a comprehensive introduction to machine learning. It builds upon fundamental concepts in mathematics, specifically probability and statistics, linear algebra, and calculus. Students will learn about supervised and unsupervised learning, various learning algorithms, and basics of learning theory, graphical models, and reinforcement learning.

4
ML7101 Probabilistic and Statistical Inference

Assumed knowledge: Basic concepts in linear algebra, calculus, probability, and statistics. Programming in Python or similar language. 

Prerequisite course: NLP701 Natural Language Processing  

Course description: This course provides a comprehensive introduction to speech processing. It builds upon fundamental concepts in speech processing and assumes familiarity with mathematical and signal processing concepts. 

4
ML710 Parallel and Distributed Machine Learning System

As Machine Learning (ML) programs increase in data and parameter size, their growing computational and memory requirements demand parallel and distributed execution across multiple network-connected machines. In this course, students will learn the fundamental principles and representations for parallelizing ML programs and learning algorithms. Students will also learn how to design and evaluate (using standard metrics) and compare between complex parallel ML strategies composed out of basic parallel ML “aspects” and evaluate and compare between the architecture of different software systems that use such parallel ML strategies to execute ML programs. Students will also use standard metrics to explain how compilation and resource management affects the performance of parallel ML programs.
Course description: The course covers the mathematical foundation of robotic systems and introduces students to the fundamental concepts of ROS (Robot Operating System) as one of the most popular and reliable platforms to program modern robots. It also highlights techniques to formally model and study robot kinematics, dynamics, perception, motion control, navigation, and path planning. Students will also learn the interface of different types of sensors, read and analyze their data, and apply it in various robotic applications. 

4
MTH7101 Mathematical Foundations of Artificial Intelligence

This course provides a comprehensive mathematical foundation for the field of artificial intelligence. It builds upon fundamental concepts in linear algebra, probability theory, statistics, and calculus. Students will learn how these mathematical concepts can be used to solve problems frequently encountered in AI applications.

4
MTH702 Optimization

This course provides a graduate-level introduction to the principles and methods of optimization, with a thorough grounding in the mathematical formulation of optimization problems. The course covers fundamentals of convex functions and sets, first order and second order optimization methods, problems with equality and/or inequality constraints, and other advanced problems.

4
MTH703 Mathematics for Theoretical Computer Science 4
NLP701 Natural Language Processing

This course provides a comprehensive introduction to natural language processing (NLP). It builds upon fundamental concepts in mathematics, specifically probability and statistics, linear algebra, and calculus, and assumes familiarity with programming.

4
NLP702 Advanced Natural Language Processing

This course provides a comprehensive introduction to natural language processing (NLP). It builds upon fundamental concepts in NLP and assumes familiarization with mathematical concepts and programming.

4
NLP703 Speech Processing

This course provides a comprehensive introduction to speech processing. It builds upon fundamental concepts in speech processing and assumes familiarization with mathematical and signal processing concepts.

4

Master’s thesis research exposes students to an unsolved research problem, where they are required to propose new solutions and contribute towards the body of knowledge. Students pursue an independent research study, under the guidance of a supervisory panel, for a period of one year.

Code Course title Credit hours
CS799 Computer Science Master's Research Thesis

Course description: Master’s thesis research exposes students to an unsolved research problem, where they are required to propose new solutions and contribute towards the body of knowledge. Students pursue an independent research study, under the guidance of a supervisory panel, for a period of one (1) year. Master’s thesis research helps train graduates to pursue more advanced research in their Ph.D. degree. Further, it enables graduates to independently pursue an industrial project involving research component independently.

8

The MBZUAl internship with industry is intended to provide the student with hands-on experience, blending practical experiences with academic learning.

Code Course title Credit hours
INT799 Internship

Assumed knowledge: Prior to undertaking an internship, students must have successfully completed 24 credit hours. 

Course description: The MBZUAI Internship (up to six weeks) with industry is intended to provide the student with hands-on experience, blending practical experiences with academic learning. 

2

Year 1

Semester 1

CB7103 Machine Learning with Python (2 CR)
CB7104 Introduction to Deep Learning (2 CR)
CB7105 Advanced Algorithms and Data Structures (4 CR)

SEMESTER 2

CS7201 Foundations of AI System Design (4 CR)
Two electives from the list (8 CR)

SUMMER

INT799 Masters Internship (2 CR)

SEMESTER 3

CB7199 Computational Biology Research Theses (4 CR)
RES799 Introduction to Research Methods (2 CR)

SEMESTER 4

CB7199 Computational Biology Research Theses (4 CR)

Disclaimer: Subject to change.


Bachelor of Science or equivalent from an accredited university or a university recognized by the UAE MoHESR. Students should have a minimum CGPA of 3.2 (on a 4.0 scale) or equivalent and provide their complete degree certificates and transcripts (in English) when submitting their application. A degree attestation (for degrees from the UAE) or an equivalency certificate (for degrees acquired outside the UAE) should also be furnished within their first semester at the university. Please visit the UAE MOE website for more details on the attestation and equalization procedures.

Each applicant must show proof of English language ability by providing valid certificate copies of either of the following:

  • TOEFL iBT with a minimum total score of 90
  • IELTS Academic with a minimum overall score of 6.5
  • EmSAT English with a minimum score of 1550
  • TOEFL iBT and IELTS Academic certificates are valid for two (2) years from the exam date, while EmSAT results are valid for eighteen (18) months.

Waiver requests are made for eligible applicants who are citizens (by passport or nationality) of the UK, USA, Australia, and New Zealand and have completed their studies from K-12 until they earned a bachelor’s degree.

The Graduate Record Examination (GRE) General score is a plus and would be considered in evaluating the applicants. (optional).

In an 800-word essay, please explain why you would like to pursue a graduate degree at MBZUAI and include the following information

  • Motivation for applying to the university
  • Personal and academic background and how it makes you suitable for the program you are applying for
  • Experience in completing a diverse range of projects related to artificial intelligence
  • Stand-out achievements, e.g. awards, distinction, etc
  • Goals as a prospective student
  • Preferred career path and plans after graduation
  • Any other details that will support the application

Selected applicants will be invited to participate in an entry exam that will include questions related to the following topics

  • Admission Interview

Prior coursework in natural sciences is considered an advantage.

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